C
About
Flatiron Health is a health technology company dedicated to transforming cancer care by building the infrastructure that connects clinical practice with research and regulatory decision-making. The platform serves a broad ecosystem of stakeholders — including oncologists, life sciences companies, academic research institutions, and regulatory agencies — by turning real-world oncology data into actionable evidence. At its core, Flatiron offers two major solution pillars: Real-World Evidence (RWE) and Point of Care technology. The RWE platform aggregates and structures longitudinal patient data from oncology practices to support drug development, regulatory submissions, and outcomes research. The Point of Care solutions provide oncology clinics with tools that streamline clinical workflows, improve documentation quality, and support evidence-based treatment decisions at the bedside. Clinicians use Flatiron's technology to manage patient journeys more effectively, while pharmaceutical and biotech companies leverage its real-world data to support clinical trials, safety monitoring, and market access strategies. Regulators rely on Flatiron evidence to supplement or replace traditional trial data in certain contexts. Flatiron Health is particularly valuable for oncology-focused organizations that need high-quality, structured cancer data at scale. Its technology is purpose-built for the complexity of cancer care, covering dozens of tumor types and treatment modalities. By connecting data across the care continuum, Flatiron accelerates the pace of cancer research and helps ensure that every patient benefits from the latest clinical insights.
Key Features
- Real-World Evidence Generation: Aggregates and structures longitudinal oncology patient data to support regulatory submissions, drug development, and clinical outcomes research.
- Point-of-Care Oncology Tools: Provides oncology clinics with workflow tools that improve clinical documentation quality and support evidence-based treatment decisions.
- Oncology-Specific Data Infrastructure: Purpose-built data platform covering dozens of tumor types and treatment modalities, enabling structured, analysis-ready cancer datasets at scale.
- Drug Development Acceleration: Supports pharmaceutical and biotech companies with real-world data for clinical trial design, safety monitoring, and market access strategies.
- Regulatory-Grade Evidence: Produces evidence meeting the quality standards required by regulatory agencies such as the FDA, enabling faster approvals and label expansions.
Use Cases
- Pharmaceutical companies use Flatiron's real-world evidence platform to generate supporting data for FDA regulatory submissions and label expansion requests.
- Oncology practices deploy Flatiron's point-of-care tools to improve clinical documentation, streamline workflows, and ensure treatment decisions are grounded in current evidence.
- Academic research institutions leverage Flatiron's structured oncology datasets to conduct outcomes research across multiple tumor types and patient populations.
- Biotech companies use Flatiron data to design smarter clinical trials by identifying eligible patient cohorts and understanding real-world treatment patterns.
- Regulators reference Flatiron-generated evidence to supplement traditional trial data when evaluating new cancer therapies for accelerated approval pathways.
Pros
- Purpose-Built for Oncology: Unlike general health data platforms, Flatiron is exclusively focused on cancer care, resulting in deeper domain expertise and higher data quality for oncology use cases.
- Spans the Entire Cancer Care Ecosystem: Serves clinicians, life sciences companies, and regulators from a single platform, enabling cross-stakeholder collaboration and data consistency.
- Regulatory-Accepted Real-World Evidence: Data and evidence generated by Flatiron have been used in regulatory submissions, giving it a high credibility benchmark for research and compliance.
Cons
- Enterprise-Only Pricing: Flatiron Health is designed for large healthcare organizations, life sciences companies, and institutions — pricing and access are not available for individual researchers or small teams.
- Narrow Domain Focus: The platform is exclusively focused on oncology, making it unsuitable for organizations working outside of cancer care.
- Integration Complexity: Deploying Flatiron's point-of-care and data solutions within existing hospital or clinic EHR infrastructure can require significant technical and operational effort.
Frequently Asked Questions
What is Flatiron Health used for?
Flatiron Health is used to generate real-world evidence from oncology patient data and to provide point-of-care technology tools for cancer clinics. Its customers include pharmaceutical companies, academic research centers, regulatory agencies, and oncology practices.
Who are Flatiron Health's primary customers?
Flatiron serves three main groups: clinicians and oncology practices seeking better care delivery tools, life sciences companies needing real-world data for drug development, and regulators requiring high-quality evidence for approval decisions.
What is real-world evidence (RWE) in the context of Flatiron?
Real-world evidence refers to clinical evidence derived from real patient data collected outside of traditional randomized controlled trials — such as electronic health records and claims data. Flatiron structures this data to make it usable for research and regulatory purposes.
Is Flatiron Health only for oncology?
Yes, Flatiron Health is exclusively focused on cancer care. Its data infrastructure, evidence platform, and point-of-care tools are all designed specifically for oncology.
How does Flatiron Health support drug development?
Flatiron provides pharmaceutical and biotech companies with structured, longitudinal real-world oncology data that can be used to design clinical trials, monitor drug safety, generate comparative effectiveness evidence, and support regulatory submissions.
