TopazTopaz is an open-source deep learning pipeline for automated particle picking and denoising in cryo-electron microscopy images using CNNs trained on positive-unlabeled examples.(0)AI Models & Infrastructure·Research & Education·AI Research Tools0
Pixie AutonomousPixie is an open-source Kubernetes observability platform using eBPF for auto-instrumentation. Monitor services, trace requests, and debug applications without changing code.(0)Data & Analytics·DevOps Tools·Command Line Tools0
Nym PrivacyNymVPN protects your metadata with mixnet technology and zero-knowledge proofs. Decentralized, can't-log design. Anonymous signup. Try free for 7 days.(0)Productivity·AI Infrastructure Tools0
Cline AICline is a free, open-source AI coding agent with Plan/Act modes, MCP integration, and CLI support. Trusted by 5M+ developers for autonomous coding, refactoring, and workflow automation.(0)AI Code Editors·Vibe Coding Tools·AI Coding Agents0
Bibino Baby MonitorBibino transforms your existing phones, tablets, and computers into a reliable baby monitor with live video, motion detection, two-way audio, and lullabies. Free to download on iOS, Android, macOS, Windows, and Linux.(0)Productivity·AI Assistants0
Pulumi AI IaCPulumi is a cloud infrastructure platform combining IaC in any language with AI automation, secrets management, and policy governance for any cloud.(0)Automation & Agents·DevOps Tools·AI Infrastructure Tools0
TheSkyXTheSkyX is professional astronomy software for telescope control, imaging, and sky charting. Available in Serious and Professional editions for Windows, macOS, and Linux.(0)Productivity·Research & Education0
Meta ESMOpen-source pretrained language models for protein sequences. Enables protein structure prediction, mutational effect analysis, and generative protein design using transformer-based architectures.(0)AI Models & Infrastructure·Foundation Models·AI Research Tools0
FreeMoCapFreeMoCap is a free, open-source markerless motion capture tool that uses standard cameras and AI-powered computer vision to capture research-grade 3D human movement data locally on your machine.(0)Data & Analytics·Research & Education·3D Modeling Tools0
RoseTTAFoldNARoseTTAFold2NA is an open-source deep learning model for predicting 3D structures of protein-DNA and protein-RNA complexes, developed by UW IPD.(0)AI Models & Infrastructure·Research & Education·AI Research Tools0
KStarsKStars is the most feature-rich free astronomy software, offering sky simulation with 100 million stars, astrophotography workflows, and observation planning for Windows, macOS, and Linux.(0)Productivity·Research & Education0
ComfyUIComfyUI is a free, open-source visual node/graph interface and API for running Stable Diffusion and other diffusion models locally with full pipeline control.(0)AI Models & Infrastructure·AI Image Generators·Art Generators0
ArdourArdour is a professional, free and open-source DAW for recording, editing, and mixing audio and MIDI on Linux, macOS, and Windows.(0)Podcast Tools·Audio Enhancers0
EX-CommandStationBuild your own DCC Command Station with Arduino. EX-CommandStation supports WiFi, Ethernet, Bluetooth, automation, turnouts, signals, and dozens of motor drivers for complete model railroad control.(0)Coding & Development·Automation & Agents·No-Code0
Wordfast ProWordfast Pro is the world's #1 platform-independent Translation Memory tool, trusted by 15,000+ translators, LSPs, and corporations. Available on Windows, Mac, Linux, and the web.(0)Writing·Productivity·Document Tools0
Tesseract OCRTesseract OCR is a free, open-source optical character recognition engine supporting 100+ languages. Extract text from images, scanned documents, and PDFs with high accuracy.(0)PDF Tools·Document AI Tools·OCR Tools0
SpeciesNetSpeciesNet is Google's open-source ensemble AI model for automatically classifying wildlife species in motion-triggered camera trap images.(0)Data & Analytics·AI Models & Infrastructure·Research & Education0
Smol DeveloperSmol Developer is an open-source AI developer agent that scaffolds entire codebases from a product spec. Embed it in your own app or use it standalone.(0)Coding & Development·Vibe Coding Tools·AI Coding Agents0
RC-AstroRC-Astro offers a suite of AI-powered astrophotography tools including BlurXTerminator, NoiseXTerminator, StarXTerminator, and more for PixInsight and Photoshop.(0)Photo Editors·Image Upscalers0
KoboldCppKoboldCpp lets you run GGUF large language models locally with a built-in KoboldAI UI and OpenAI-compatible API. No installation needed — just download and run on Windows, Linux, macOS, or Android.(0)AI Models & Infrastructure·AI Chatbots·LLM Developer Tools0