About
Akili Interactive is pioneering a new class of prescription digital medicines designed to treat cognitive impairments through captivating video game experiences. By combining world-class neuroscience with cutting-edge technology and game design, Akili challenges the conventional model of medicine delivery — no pills, no syringes, just scientifically validated interactive experiences. Their flagship product, EndeavorRx, is the first FDA-authorized prescription video game treatment specifically indicated for children with ADHD, available through a doctor's prescription. Building on that clinical foundation, Akili launched EndeavorOTC — a game-based treatment clinically proven to improve attention and focus in adults with ADHD, now available directly on the App Store and Google Play without a prescription. The company's approach merges rigorous scientific and clinical research with the engagement mechanics of modern gaming, creating medicine that patients can actually enjoy taking. Akili's pipeline addresses a wide spectrum of cognitive conditions, with ongoing research into areas such as COVID-related brain fog and broader neurological disorders. Akili is targeted at patients, caregivers, and clinicians looking for innovative, evidence-based digital alternatives to traditional pharmacological treatments for ADHD and cognitive dysfunction. Their work represents a broader movement toward software-as-medicine — redefining what therapeutic intervention can look like in the digital age.
Key Features
- EndeavorRx – FDA-Authorized for Children: The first FDA-authorized prescription video game treatment for children with ADHD, available through a licensed clinician's prescription.
- EndeavorOTC – Adult ADHD Treatment: A clinically proven, over-the-counter game-based treatment to improve attention and focus in adults with ADHD, available on iOS and Android.
- Neuroscience-Backed Game Design: Proprietary cognitive training mechanics developed from rigorous neuroscience research, embedded within an engaging video game format.
- Prescription Digital Medicine Pipeline: Active research and development targeting COVID brain fog, workplace ADHD, and additional cognitive health conditions beyond initial indications.
- Clinical Rigor & Regulatory Validation: Products are supported by published clinical studies and subject to FDA oversight, ensuring safety and efficacy standards on par with traditional medicine.
Use Cases
- Children aged 8–12 diagnosed with ADHD using EndeavorRx as part of a clinician-supervised treatment plan to improve sustained attention.
- Adults with ADHD seeking a non-pharmacological, game-based method to enhance focus and cognitive performance in daily and professional life.
- Pediatricians and child psychiatrists recommending a complementary digital therapy alongside behavioral or pharmacological ADHD treatment.
- Researchers and clinical teams studying cognitive impairments such as COVID-related brain fog leveraging Akili's digital medicine platform.
- Healthcare organizations and employers exploring innovative digital therapeutics to support workforce cognitive health and ADHD management.
Pros
- First-of-its-Kind FDA Authorization: EndeavorRx holds the distinction of being the first FDA-authorized prescription video game, lending significant clinical credibility to the platform.
- Non-Pharmacological Treatment Option: Provides patients and caregivers a drug-free alternative or complement to traditional ADHD medications, reducing concerns about side effects.
- Engaging Patient Experience: Game-based delivery increases patient adherence compared to conventional therapies, especially among children who benefit from intrinsic motivation.
- Accessible OTC Option for Adults: EndeavorOTC removes prescription barriers for adults seeking cognitive support, making the treatment more widely accessible.
Cons
- Paid / Insurance Coverage Uncertainty: As a relatively novel category of medicine, insurance reimbursement for digital therapeutics may be inconsistent or unavailable for some patients.
- Narrow Current Indications: Products are currently focused on ADHD; broader cognitive conditions are still in research or development stages and not yet commercially available.
- Requires Device & Internet Access: As a digital-only treatment, patients need a compatible smartphone and connectivity, which may exclude some populations.
Frequently Asked Questions
What is EndeavorRx and who is it for?
EndeavorRx is the first FDA-authorized prescription video game treatment designed for children ages 8–12 with ADHD. It requires a prescription from a licensed healthcare provider and is used as part of a broader treatment plan.
What is EndeavorOTC and how is it different from EndeavorRx?
EndeavorOTC is an over-the-counter game-based treatment for adults with ADHD. Unlike EndeavorRx, it does not require a prescription and can be downloaded directly from the App Store or Google Play.
Is Akili's digital medicine scientifically validated?
Yes. Akili's products are developed with clinical and scientific rigor, backed by published peer-reviewed research and regulatory review by the FDA.
Can Akili's treatments replace traditional ADHD medication?
Akili's digital medicines are designed to be used as standalone treatments or as complements to existing therapies. Patients should consult their physician before making any changes to their treatment plan.
What platforms are Akili's products available on?
EndeavorOTC is available on iOS (App Store) and Android (Google Play). EndeavorRx is also a mobile application distributed through healthcare providers.
