Strand NGS

paid

Strand NGS is an integrated NGS data analysis platform supporting RNA-Seq, DNA-Seq, ChIP-Seq, Methyl-Seq, MeDIP-Seq, and small RNA-Seq with rich visualizations and biological interpretation tools.

Data & Analytics

Research & Education

AI Research Tools

About

Strand NGS is an end-to-end next-generation sequencing (NGS) data analysis platform developed by Strand Life Sciences. Formerly known as Avadis NGS, it provides researchers with a unified suite of tools covering alignment, quality control, statistical analysis, biological interpretation, and interactive visualization of genomics data. The platform supports a wide range of experimental workflows: RNA-Seq for differential gene expression and novel splice junction discovery; DNA-Seq for variant detection, structural variants, and copy number variations (CNVs); ChIP-Seq for identifying transcription factor binding sites and histone modification sites using PICS and MACS algorithms; Small RNA-Seq for detecting differentially expressed small RNAs and identifying mRNA targets; Methyl-Seq and MeDIP-Seq for studying differentially methylated regions and cytosines. Strand NGS includes a powerful genome browser for visualizing annotations across multiple genomic regions and zoom levels, along with rich visualizations for mapping quality, variant support, and coverage analysis. Its biological interpretation module leverages canonical pathway databases and literature to uncover gene interaction networks. A dedicated Server Edition enables multi-member research teams to collaborate on shared NGS datasets in an enterprise setting. The software is available via installer and offers a free 20-day trial, making it accessible for academic and commercial genomics laboratories seeking a desktop-based, integrated NGS analysis solution.

Key Features

Multi-Workflow NGS Support: Supports comprehensive workflows for RNA-Seq, DNA-Seq, ChIP-Seq, Small RNA-Seq, Methyl-Seq, and MeDIP-Seq experiments in a single integrated platform.
Alignment & Data Quality Control: Identifies and filters reads with poor mapping and alignment qualities to ensure high-confidence downstream results.
Interactive Genome Browser: Visualizes genomic annotations, variants, coverage, and mapping quality across multiple regions at adjustable zoom levels.
Biological Interpretation & Pathway Analysis: Uses canonical pathway databases and literature-derived gene interaction networks to provide biological context for sequencing results.
Server Edition for Teams: A collaborative server deployment designed for multi-member research teams working concurrently on shared NGS datasets.

Use Cases

Academic genomics researchers performing differential gene expression analysis from RNA-Seq experiments.
Clinical research labs detecting single nucleotide variants (SNVs) and structural variants from DNA-Seq data.
Epigenetics teams studying DNA methylation patterns using Methyl-Seq or MeDIP-Seq workflows.
ChIP-Seq studies identifying transcription factor binding sites and histone modifications in regulatory genomics.
Multi-investigator genomics cores managing and analyzing shared NGS datasets using the Server Edition.

Pros

All-in-One Platform: Covers the entire NGS analysis pipeline—from raw read alignment to biological interpretation—eliminating the need for multiple disconnected tools.
Broad Assay Support: Handles six major NGS assay types in a single software package, making it versatile for diverse genomics research needs.
Rich Visualizations: Built-in genome browser and quality visualization tools give researchers intuitive, interactive access to complex sequencing data.
Team Collaboration via Server Edition: The Server Edition enables enterprise and institutional labs to centralize data management and enable collaborative workflows.

Cons

Paid Software with Limited Trial: Only a 20-day free trial is offered; ongoing use requires a commercial license, which may be a barrier for smaller labs or individual researchers.
Desktop-Centric Workflow: Primarily installer-based, which may limit flexibility for cloud-native or web-based bioinformatics pipeline integrations.
Niche Focus: Designed specifically for NGS genomics research, making it unsuitable for non-sequencing data analysis or general bioinformatics tasks.

Frequently Asked Questions

Strand NGS supports RNA-Seq, DNA-Seq, ChIP-Seq, Small RNA-Seq, Methyl-Seq, and MeDIP-Seq workflows, covering differential expression, variant detection, methylation analysis, and more.

Strand NGS offers a free 20-day trial. After the trial period, a paid license is required to continue using the software.

The Server Edition is designed for multi-member research teams and allows collaborative access to shared NGS datasets on a central server, while the standard edition is for individual or small-scale use.

Strand NGS is available via downloadable installers for desktop environments (Windows, macOS, Linux) and also offers a server-based deployment for team use.

Strand NGS was formerly known as Avadis NGS. It is the same product rebranded and further developed by Strand Life Sciences.